I do. I love the feeling of my fat jiggling and wobbling as I move, unhindered by clothes. Most of my clothes are pretty tight now so they tend to hold it in to some degree.
I really don't prefer nudity, that being said, I do wear minimum clothes alone at home. I usually wear the smallest briefs (bikini cut) that I can fit into and a very tight t-shirt. I feel fatter with tight clothes on.
My wife and I spend most evenings around here naked, or at best with just boxer shorts on. Heater on during the winter months, of course. It's quite liberating And in her case, she's just sexier naked....with her 325 pounds and 46DDD chest allowed to be free!