Cyproheptadine's half life is twice as long as Diphenhydramine. So you can often get by with only one daily dose.

Apetamin is an antihistamine with no discernible difference from any first generation antihistamine like Diphenhydramine, what is in Benadryl.

They both act on the H1 receptors causing appetite increase. Those with allergies that have been on antihistamines for years are often over weight because of this. Simply Google 'Benadryl' and 'munchies/starving'

They can obviously cause sleepiness/laziness as a side effect.

I was at a 4th of July BBQ last night and there was this massive mom (400lbs) and I was blown away how much she ate; literally ate the entire time we were there - always had a new plate in her hand. No exaggeration, atleast 7 giant burgers, 4 hot dogs and countless never ending finger food plates. On top of that she probably had atleast 5 large sugary margaritas.

All of the moms were overweight except for the younger married 20 somethings. But you can already tell with how much they were packing in, that 10 years from now they'll be part of the club: plopped down 250lbs enjoying life.

All of the heavy moms end up congregating by the food table over the span of the night and stuff their faces together, chatting, laughing while the dads are out playing basketball and tee ball w/the kids. The wives just get drunk and stuffed – YET, at the end of the night it's the women that all look so exhausted but all they've been doing is sitting and eating!

Seems we agree that the quickest way to get fat is combining carbs with fats. Specifically carbs that spike insulin the highest (highly glycemic, simple carbs) which tend to be junk food or "empty calories". What hasn't been brought up is the reason: insulin.

Why? Insulin is the hormone that shuttles broken down food into muscle and fat cells by "telling" the cells to open up and absorb them. This is why all bodybuilders shoot up insulin after their workouts and avoid fatty foods after their insulin shots: the insulin pounds protein into the muscle cells at a rate a natural lifter could never replicate causing massive unnatural growth.

For those that are obese, when you spike insulin with sugars and simple carbs, the insulin then signals 'storage' to the body's cells, opens the fat cells and packs on all of the fats consumed in the same meal at a significantly higher rate.

The drug is odd because it melts your anxieties away and enhances the taste of food so dramatically that most on it weirdly find they don't seem to care they're gaining weight. They feel so much better and food becomes such an amazing obsession. Read the reviews of Zyprexa; folks fantasizing about what they'll eat tomorrow. It shuts down the H1 & H2 receptors in the brain so you can never feel full no matter how much you've eaten - patients will eat to to the point they vomit and then simply continue eating.

I'm not buying into anything. I've done a Keto diet for the last couple years and frankly after lots of experimentation I'm not a huge believer in the Atkins/Keto diet. The water weight shed in the first 1-2 weeks cutting carbs is what gives folks the encouragement that they're losing "weight" faster. After that, it's the same long slog of weight loss seen in a caloric deficit on any other diet. And depending on how low your carb consumption is, the diet itself can yield low blood sugar, carb cravings and binge eating.

The ONLY time I get overwhelming sugar cravings is when I'm on Keto/Atkins.

That said, I think it's effectiveness for those that are obese is that it forces them out of the binge-crash cycle of sugar consumption that drives folks into weight gain.

In the end, a calorie is a calorie. I've seen people gain tons of body fat consuming too much protein via whey shakes. All I'm saying is that there are over double the calories in a gram of fat than a gram of sugar. Why do you think people around here with the most profound results are chugging heavy cream?

Well, nothing makes you fatter faster than fat:

1g protein = 4 calories
1g carb = 4 calories
1g fat = 9 calories

Yes, they can seem more filling. They key is to combine them with fast acting carbs because the insulin response and crash from the carbs will trigger you to be hungry again.

But nothing holds a candle to true fat which is why it's fried foods, heavy cream, butter that make people blow up. A lot of people think of sugar - but fat is over double the calories of sugar and is what truly makes sweets fattening (all of the butter and oils).

I often think about this when eating at Buffalo Wild Wings and Buffalo Wings & Rings. We go there at least 1-2x a week and virtually everybody in the restaurant is a couple/family where the wife is 250-300lbs+ and the guy is a slender/fit dude.

And as I survey the other tables, I feel like my wife and I are all there doing the same thing: I'm casually catching a sports game while my wife is in her own world eating multiple appetizers, slamming beers to the point she can't move.

You get all these couples that eat appetizers and drink for a good 90 min before they even put in their order for a meal. They often are there with other couples as a group and it's the same thing: all of the wive's are well over 300lbs and it's like they egg each other on with the stuffing while the husbands just nurse beers and chat. All of the wives will get cake at the end again while the husbands pass.

You look around and it's one giant stuffing session for these gaining housewives - taking breaks between another 20min of stuffing and ordering.

The one that gets me are the husbands ordering an appetizer for the wife AFTER the giant meal while he finishes his last beer. Who the hell does that? Just seems so feeder'ish to me!

The type of food will/can not determine where the fat will go. It's purely based on your genetics.

Let her do her thing. Personally, it was the process of my wife trying to lose weight that forced her to face the reality that she is and wants to be a glutton. Even after she had shed a large amount and had run a couple 5K's, she knew she wanted wings and beer more. At the time I assumed feeding/gaining would have to stay a fantasy in my life. But then she finally reverted back to the foods she loves and became open to gaining weight.

But this is something only she can figure out.